TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window
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چکیده
منابع مشابه
Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas.
Chemotherapy and radiation therapy for cancer often have severe side effects that limit their efficacy. Glucocorticoids (GCs) are frequently used as cotreatment because they may have potent proapoptotic properties and reduce nausea, hyperemesis, and acute toxicity on normal tissue. In contrast to the proapoptotic effect of GCs in lymphoid cells, resistance toward cancer therapy-mediated apoptos...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2007
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.21555